CancerVar for improved clinical interpretation of somatic mutations facilitated by machine learning

CancerVar is a bioinformatics software tool for clinical interpretation of genetic variants by machine learning. The input to CancerVar is an annotated file generated from ANNOVAR, while the output of CancerVar is the classification of variants into 'Tier I: Variants of Strong Clinical Significance','Tier II: Variants of Potential Clinical Significance','Tier III: Variants of Unknown Clinical Significance' and 'Tier IV: Benign or Likely Benign Variants', together with detailed evidence.


Search your exonic variants from pre-built Cancervar databases(updated on with 8M sites in 1500 cancer census gene):

If you already know the criteria of your variant, you can clik here to interpret your variant directly.
This server is for exon variants and some known indels interpretation only, if you have novel indels, you need to download the cancervar tool from github, then interpret your variant on local.


Please select the genomic version:
and cancer types:


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